The objective of the paper is to study the influence of Semen Oryzae cum Monasco ( SOM) on BMP-2 expression of rat osteoblasts cultivated in vitro and thus to offer the cytological basis for the development of the new TCD for treating osteoporosis. 为研究红曲对体外培养大鼠成骨细胞BMP-2表达的影响,从而为治疗骨质疏松症开发出中药新药提供细胞学依据。